Error when trying to send mails using smtp

Error when trying to send mails using smtp

I have got the following error message when i tried to sent message using
smtp.
A connection attempt failed because the connected party did not properly
respond after a period of time, or established connection failed because
connected host has failed to respond 67.69.240.69:25
System.Net.WebException: Unable to connect to the remote server --->
System.Net.Sockets.SocketException: A connection attempt failed because
the connected party did not properly respond after a period of time, or
established connection failed because connected host has failed to respond
67.69.240.69:25
at System.Net.Sockets.Socket.DoConnect(EndPoint endPointSnapshot,
SocketAddress socketAddress)
at System.Net.ServicePoint.ConnectSocketInternal(Boolean
connectFailure, Socket s4, Socket s6, Socket& socket, IPAddress&
address, ConnectSocketState state, IAsyncResult asyncResult, Int32
timeout, Exception& exception)
--- End of inner exception stack trace ---
at System.Net.ServicePoint.GetConnection(PooledStream PooledStream,
Object owner, Boolean async, IPAddress& address, Socket& abortSocket,
Socket& abortSocket6, Int32 timeout)
at System.Net.PooledStream.Activate(Object owningObject, Boolean async,
Int32 timeout, GeneralAsyncDelegate asyncCallback)
at System.Net.PooledStream.Activate(Object owningObject,
GeneralAsyncDelegate asyncCallback)
at System.Net.ConnectionPool.GetConnection(Object owningObject,
GeneralAsyncDelegate asyncCallback, Int32 creationTimeout)
at System.Net.Mail.SmtpConnection.GetConnection(String host, Int32 port)
at System.Net.Mail.SmtpClient.Send(MailMessage message)
--- End of inner exception stack trace ---
at System.Net.Mail.SmtpClient.Send(MailMessage message)
at Handler.BLL.cSendMail.SendMail(String p_strFrom, String
p_strDisplayName, String p_strTo, String p_strSubject, String
p_strMessage, String strFileName)
[ staffID:,21/08/2013 9:49:34 AM ]: status code : GeneralFailure